Flu-turistic: Scientists create superflu vaccine that can fight 20 strains

Scientists have created a supervaccine that can fight all known flu strains and uses the same technology as Covid shots.

The experimental vaccine, which has not yet been tested in humans, provided broad protection against 20 subtypes of influenza A and B in animal trials.

But Professor John Oxford, a virologist at Queen Mary University in London, said the new vaccine developed at the University of Pennsylvania represented a “huge breakthrough.”

The two frames use mRNA technology that was first applied during the pandemic. modern as well as pfizervaccines for Covid.

It works by providing instructions that teach cells to make replicas of proteins that appear on all surfaces of the influenza virus.

This trains the body to remember how to recognize and fight off any foreign invaders carrying this protein in the future.

It is hoped that the universal vaccine will give people a baseline level of immunity that will reduce the number of hospitalizations and deaths every year.

It would also take the guesswork out of developing annual shots a few months before the flu season each year.

Currently, vaccine decisions are made based on: which influenza viruses are infecting people ahead of the upcoming influenza season; how these viruses spread; and how well the body is prepared to deal with these flu viruses based on previous season’s vaccinations.

It happens among the largest influenza outbreak in the United States in ten years it is the overcrowding of hospitals and the closure of schools across the country.

The H3N2 strain is currently wreaking havoc and tends to hit the elderly and the very young the hardest.

There is currently no vaccine against H3N2 infection.

According to the Centers for Disease Control and Prevention (CDC), scientists have taken some steps to start developing a vaccine, but there is no consensus on mass production.

The vaccine contains genetic coding instructions for 20 known flu subtypes. When injected into the body, the cells will make copies of the proteins that appear with every type of flu. They trigger an immune response when the body creates and remembers antibodies for each influenza subtype. The immune response may be withdrawn if the body encounters the flu in the future.

While the new vaccine could stop future flu pandemics, it won’t be a panacea because it will reduce severe illness and death, but it won’t completely prevent infections.

Researchers at the University of Pennsylvania School of Medicine have only tested the vaccine in mice and ferrets, but are currently planning human trials and the first data sets could be available within the next six months.

The researchers found that vaccine-induced antibody levels remained unchanged for at least four months in the animals tested.

Professor Oxford said: “I can’t stress enough what a breakthrough this article is.”

He added that there is a “very good chance” that the injection will work on humans.

According to him, a shot could save thousands of lives.

“The potential is huge and I think we sometimes underestimate these large respiratory viruses.”

‘I’ve never seen anything like it’: Doctors warn America is running out of FOUR children’s antibiotics and flu medicine as kids suffer from ‘triple sickness’

America is short of four essential antibiotics and respiratory drugs for children as seasonal microbes return with renewed vigor after being suppressed during lockdowns.

Health officials said there was a shortage of amoxicillin, a life-saving antibiotic used to treat bacterial infections such as pneumonia, respiratory infections and strep throat.

But doctors on the ground are also reporting depleted stocks of Augmentin, an antibiotic that uses amoxicillin along with clavulanic acid, Tamiflu, the most commonly used flu medication in U.S. hospitals, and albuterol, an inhaler for asthma and to relieve other lung symptoms.

Desperate parents report walking from pharmacy to pharmacy for hours looking for medicines for their children.

The shortage is caused by growing demand. Several children’s hospitals have already reached 100 percent capacity as the incidence of RSV and influenza, which kills children, is at its highest level in a decade at this time of year.

Senior study author Dr. Scott Hensley, a professor of microbiology at the university, said: “The idea here is to create a vaccine that will give people a baseline level of immune memory to different flu strains, so there will be far fewer illnesses and deaths. When will the next flu pandemic occur?

He added: “We believe this vaccine can significantly reduce the chances of ever getting a severe flu infection.”

The new jab uses a piece of genetic code called mRNA and gives instructions to cells that allow them to make replicas of the so-called hemagglutinin proteins that appear on the surface of the influenza virus.

They stimulate an immune response where the body makes and remembers antibodies for each influenza virus.

Current flu shots can’t do that because they rely on a tiny physical part of a weakened flu strain.

The vaccine is not expected to completely stop people from getting the flu, but it does reduce the chance of serious illness and death from new variants of the virus.

This means that people will be effectively immunized against 20 types of influenza at one time.

The Moderna and Pfizer-BioNTech Covid vaccines are mRNA injections, an underutilized technology before it became widespread during the pandemic.

Victor Jiménez Cid, professor in the Department of Microbiology and Parasitology at the Faculty of Pharmacy at the Complutense University of Madrid, said: “This is the first high-impact publication that presents a successful strategy for creating an mRNA-based “universal” influenza vaccine. ‘

He added: “So this type of vaccine will prevent, in addition to seasonal flu… the possible emergence of new pandemic viruses.”

The study was published in the journal The science.